300 research outputs found
VisIVOWeb: A WWW Environment for Large-Scale Astrophysical Visualization
This article presents a newly developed Web portal called VisIVOWeb that aims
to provide the astrophysical community with powerful visualization tools for
large-scale data sets in the context of Web 2.0. VisIVOWeb can effectively
handle modern numerical simulations and real-world observations. Our
open-source software is based on established visualization toolkits offering
high-quality rendering algorithms. The underlying data management is discussed
with the supported visualization interfaces and movie-making functionality. We
introduce VisIVOWeb Network, a robust network of customized Web portals for
visual discovery, and VisIVOWeb Connect, a lightweight and efficient solution
for seamlessly connecting to existing astrophysical archives. A significant
effort has been devoted for ensuring interoperability with existing tools by
adhering to IVOA standards. We conclude with a summary of our work and a
discussion on future developments
A Catalog of Very Isolated Galaxies from the SDSS Data Release 1
We present a new catalog of isolated galaxies obtained through an automated
systematic search. These 2980 isolated galaxies were found in approximately
2099 sq deg of sky in the Sloan Digital Sky Survey Data Release 1 (SDSS DR1)
photometry. The selection algorithm, implementing a variation on the criteria
developed by Karachentseva in 1973, proved to be very efficient and fast. This
catalog will be useful for studies of the general galaxy characteristics. Here
we report on our results.Comment: 67 pages, which includes 14 figures. Accepted for publication by A
Tuberculin screening of some selected Fulani lactating cows in north-central Nigeria
The prevalence of mycobacterial infection among lactating Fulani cows was investigated in the Federal Capital Territory, Abuja and Kaduna State of Nigeria. Tuberculin testing using single comparative intradermal tuberculin test showed a 14.6 % positive, 4 % doubtful, and 81.4 % negative reactors. Mycobacterial infection was found to be present in the nomadic (constantly moving) and seminomadic (limited movement) management systems studied but management showed no significant effect on the prevalence of the disease. However, the prevalence was significantly higher in older age groups than the younger ones (P < 0.05).Peer reviewedSubmitted Versio
The AMIGA sample of isolated galaxies. IV. A catalogue of neighbours around isolated galaxies
Studies of the effects of environment on galaxy properties and evolution
require well defined control samples. Such isolated galaxy samples have up to
now been small or poorly defined. The AMIGA project (Analysis of the
interstellar Medium of Isolated GAlaxies) represents an attempt to define a
statistically useful sample of the most isolated galaxies in the local (z <
0.05) Universe. A suitable large sample for the AMIGA project already exists,
the Catalogue of Isolated Galaxies (CIG, Karachentseva 1973; 1050 galaxies),
and we use this sample as a starting point to refine and perform a better
quantification of its isolation properties. Digitised POSS-I E images were
analysed out to a minimum projected radius R > 0.5 Mpc around 950 CIG galaxies
(those within Vr = 1500 km s-1 were excluded). We identified all galaxy
candidates in each field brighter than B = 17.5 with a high degree of
confidence using the LMORPHO software. We generated a catalogue of
approximately 54 000 potential neighbours (redshifts exist for 30% of this
sample). Six hundred sixty-six galaxies pass and two hundred eighty-four fail
the original CIG isolation criterion. The available redshift data confirm that
our catalogue involves a largely background population rather than physically
associated neighbours. We find that the exclusion of neighbours within a factor
of four in size around each CIG galaxy, employed in the original isolation
criterion, corresponds to Delta Vr ~ 18000 km s-1 indicating that it was a
conservative limit. Galaxies in the CIG have been found to show different
degrees of isolation. We conclude that a quantitative measure of this is
mandatory. It will be the subject of future work based on the catalogue of
neighbours obtained here.Comment: Accepted by A&A, 10 pages, 8 figures, 4 table
Эндометриоз-ассоциированное бесплодие
БЕСПЛОДИЕ ЖЕНСКОЕЭНДОМЕТРИО
Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study
Background: Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor requirement. In the present prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock 1 (, AdrenOSS-1) study, we assessed relationships between circulating bio-ADM during the initial intensive care unit (ICU) stay and short-term outcome in order to eventually design a biomarker-guided randomized controlled trial. Methods: AdrenOSS-1 was a prospective observational multinational study. The primary outcome was 28-day mortality. Secondary outcomes included organ failure as defined by Sequential Organ Failure Assessment (SOFA) score, organ support with focus on vasopressor/inotropic use, and need for renal replacement therapy. AdrenOSS-1 included 583 patients admitted to the ICU with sepsis or septic shock. Results: Circulating bio-ADM levels were measured upon admission and at day 2. Median bio-ADM concentration upon admission was 80.5 pg/ml [IQR 41.5-148.1 pg/ml]. Initial SOFA score was 7 [IQR 5-10], and 28-day mortality was 22%. We found marked associations between bio-ADM upon admission and 28-day mortality (unadjusted standardized HR 2.3 [CI 1.9-2.9]; adjusted HR 1.6 [CI 1.1-2.5]) and between bio-ADM levels and SOFA score (p < 0.0001). Need of vasopressor/inotrope, renal replacement therapy, and positive fluid balance were more prevalent in patients with a bio-ADM > 70 pg/ml upon admission than in those with bio-ADM ≤ 70 pg/ml. In patients with bio-ADM > 70 pg/ml upon admission, decrease in bio-ADM below 70 pg/ml at day 2 was associated with recovery of organ function at day 7 and better 28-day outcome (9.5% mortality). By contrast, persistently elevated bio-ADM at day 2 was associated with prolonged organ dysfunction and high 28-day mortality (38.1% mortality, HR 4.9, 95% CI 2.5-9.8). Conclusions: AdrenOSS-1 shows that early levels and rapid changes in bio-ADM estimate short-term outcome in sepsis and septic shock. These data are the backbone of the design of the biomarker-guided AdrenOSS-2 trial. Trial registration: ClinicalTrials.gov, NCT02393781. Registered on March 19, 2015
Determinants in early life for asthma development
A reliable screening test in newborns for the subsequent development of bronchial asthma (BA) has not been found yet. This is mainly due to the complexity of BA, being made up by different types and underlying mechanisms. In different studies, a number of risk factors for BA have been identified. These include a positive family history of BA, passive smoking (also during pregnancy), prematurity (including pulmonary infections, RDS and BPD), early viral respiratory infections (such as RSV-bronchiolitis), male gender, early lung function abnormalities and atopic constitution. The major risk factor for persistent BA is an underlying allergic constitution. Therefore, early symptoms and markers of allergy (i.e. The Allergic March) and a positive family history for allergy should be considered as important risk factors for the development of BA
Adaptive servoventilation improves cardiac function and respiratory stability
Cheyne–Stokes respiration (CSR) in patients with chronic heart failure (CHF) is of major prognostic impact and expresses respiratory instability. Other parameters are daytime pCO2, VE/VCO2-slope during exercise, exertional oscillatory ventilation (EOV), and increased sensitivity of central CO2 receptors. Adaptive servoventilation (ASV) was introduced to specifically treat CSR in CHF. Aim of this study was to investigate ASV effects on CSR, cardiac function, and respiratory stability. A total of 105 patients with CHF (NYHA ≥ II, left ventricular ejection fraction (EF) ≤ 40%) and CSR (apnoea–hypopnoea index ≥ 15/h) met inclusion criteria. According to adherence to ASV treatment (follow-up of 6.7 ± 3.2 months) this group was divided into controls (rejection of ASV treatment or usage <50% of nights possible and/or <4 h/night; n = 59) and ASV (n = 56) adhered patients. In the ASV group, ventilator therapy was able to effectively treat CSR. In contrast to controls, NYHA class, EF, oxygen uptake, 6-min walking distance, and NT-proBNP improved significantly. Moreover, exclusively in these patients pCO2, VE/VCO2-slope during exercise, EOV, and central CO2 receptor sensitivity improved. In CHF patients with CSR, ASV might be able to improve parameters of SDB, cardiac function, and respiratory stability
Dark energy survey year 1 results: The lensing imprint of cosmic voids on the cosmic microwave background
Cosmic voids gravitationally lens the cosmic microwave background (CMB) radiation, resulting in a distinct imprint on degree scales. We use the simulated CMB lensing convergence map from the Marenostrum Institut de Ciencias de l’Espai (MICE) N-body simulation to calibrate our detection strategy for a given void definition and galaxy tracer density. We then identify cosmic voids in Dark Energy Survey (DES) Year 1 data and stack the Planck 2015 lensing convergence map on their locations, probing the consistency of simulated and observed void lensing signals. When fixing the shape of the stacked convergence profile to that calibrated from simulations, we find imprints at the 3σ significance level for various analysis choices. The best measurement strategies based on the MICE calibration process yield S/N ≈ 4 for DES Y1, and the best-fitting amplitude recovered from the data is consistent with expectations from MICE (A ≈ 1). Given these results as well as the agreement between them and N-body simulations, we conclude that the previously reported excess integrated Sachs–Wolfe (ISW) signal associated with cosmic voids in DES Y1 has no counterpart in the Planck CMB lensing map
- …